The molecular response of an organism -- be it mouse or man -- to pathogenic invasion is controlled by circadian rhythms, researchers found. In mice exposed to infection at the highest and lowest time of activity in the 24-hour light-dark cycle of an immune protein known as toll-like receptor 9 (TLR9), those whose exposure was at the nadir of TLR9 expression had much more severe sepsis, according to Erol Fikrig, MD, ... (read more)
Researchers of VIB and UGent have discovered a new approach to preventing septic shock, an often fatal extreme inflammatory reaction of the body. It is the most frequent cause of death at intensive care departments in hospitals. In sepsis, acute inflammation is attended by low blood pressure and blood clots, causing the organs to stop working. Only recently, the Brazilian f... (read more)
Immunity is a monthly journal which publishes research articles and reviews of general interest in the entire discipline of immunology.
http://www.elsevier.com/wps/find/journaldescription.cws_home/621182/description
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